Posted by papillon2 on August 6, 2012, at 12:00:24
In reply to Re: To all treatment-resistant people! » slabicki, posted by papillon2 on August 6, 2012, at 5:47:33
> There are a number of experimental treatments in the works. Things like ketamine, rTMS, the use of psychostimulants as adjuncts. Perhaps look into these?
Sorry, I just read from your original post that you have already tried TMS.
I'm really just throwing things out there and hoping something sticks, but are there any meds you tried years ago (at least five, ten) which didn't do much at the time? Would you be willing to try them again?
I read a first-hand response from a guy who had run the gamut of different medications for depression, multiple meds in all the different classes, combinations with mood stabilizers, anti-psychotics, etc. Most had worked for a time before pooping out. ECT had worked well previously and he was considering another round.
His family doctor wanted him to do a trial of one of the more common SSRIs (Prozac or Zoloft, can't recall which) before having ECT and he thought he'd humor him since he had nothing to lose. He wasn't expecting anything though, as he'd had given it two separate trials a decade or more ago and it hadn't done anything at the time. Well... surprise! His depression went into remission.
I found this story extremely bizarre (my initial response being WTF?!) given that his depression was obviously severe enough to warrant ECT yet the 'big guns' of meds weren't helping. But hey, the brain is a mysterious organ, maybe the opposite of a 'poop out' can happen?
Anyway, just thought I'd mention it. Feel free to dismiss as wacky. I'm still not quite sure what to think about it.
Ring the bells that still can ring
forget your perfect offering
there is a crack in everything
that's how the light gets in
~ Leonard Cohen