Posted by Alexei on May 11, 2012, at 8:00:50
In reply to Re: Abilify making my depression worse! .. for real?? » Alexei, posted by phidippus on May 10, 2012, at 19:37:55
Thank you both. Vyvanse would be considered a full dopamine agonist, correct? At which dopamine receptors? And abilify would antagonize different dopa receptors? There is no overlap?
Maybe the fact that abilify is throttling my thinking is why the vyvanse seems less effective.
Which other meds are 5ht1a antagonists? May I ask by what mechanism can abilify worsen depression? Dopamine antagonism?
> Abilify helps with depression by antagonizing 5ht1a receptors. Unfortunately it has the possible side effecct of worsening depression.
> You can continue to take Vyvanse while you are on Abilify. Neither medication contraindicates the other.
> Antagonizing dopa may not have any value for you.