Posted by CharlesRX on May 6, 2012, at 16:22:01
In reply to Re: Amisulpride for Anxiety (only), posted by bleauberry on May 5, 2012, at 10:44:09
> When anxiety issues are not managed well by first line choices, that tells me the next place to look, and hardly ever is, is the adrenals. If cortisol is too low there will be a sort of anxiety that does not respond well to meds, and if cortisol is too high the anxiety is similar but usually responds a little better to meds. Either way, some rebalancing needs to be done. I am not aware of any meds that do that. Meds are only directed at symptoms not cause. There are botanical meds that do the job well. First choice would be rhodiola rosea, second choice eleuthero, third choice ashwaganda. or any combination of two of them. In my experience ashwaganda is the best for fastest anxiety knockdown, rhodiola is the best when depression is a coexisting issue but it takes more time to work, and eleuthero is a good one it just doesn't like me.
> I have been on amisulpride several times. I did find it worked good for social anxiety but I'm not sure how well it would work with physical anxiety because I didn't really have much of that at the time. When it does work for anxiety, it really doesn't start to make a real difference until week 2 to 3. Prior to that it could actually stimulate things a little, but that passes and adjusts.
> Dosage. The higher the dose you take the more calming it will be, just like any other antipsychotic basically. For depression, doses in literature are about 50mg but in the real world everyone I have communicated with agreed that was too high. Better doses have been 25mg once a day or even once every other day, and I've even had decent results from 12.5mg, though that dose is a little more stimulatory than calming.
> I think amisulpride is worth a shot, it could work, but the main focus should be in a place you probably never suspected....adrenal herbs. You can do both at the same time. The herbs are more of a longterm healing and balancing thing that don't cover up symptoms but eliminate whatever is haywire causing them. In difficult to treat anxiety issues, that in my opinion is the most likely place to look and also the most unlikely place someone will look.
You think I'd be better off with a lower dosages (50mg or less) or a higher one (50 to 200mg)
Papers and doctors all agree that amisulpride is dopaminergic up to 200mg
What do you think?