Posted by g_g_g_unit on May 1, 2012, at 3:47:09
In reply to parnate and adhd, posted by g_g_g_unit on April 27, 2012, at 2:34:49
Scott, I've seen a couple of people in the archives (including Chairman_MAO) referring to Parnate's 'amphetamine-like' metabolites becoming active at a certain dose (I think 100mg+). Are you aware of any data backing this up, and how these metabolites might differ to the stimulant effect experienced at lower doses?
I feel like I'm at a bit of a crossroads. My psychiatrist is really happy that I'm experiencing an improvement in ADHD on Parnate, but from what I understand (according to board members etc. and also Dr Gilman), this 'stimulant' effect is more than likely going to disappear. The maximum he'll prescribe is 60mg and he won't co-administer a stimulant. Financially and logistically, trying to reach a 100mg+ dose on my own seems impossible. I e-mailed that TRD specialist and asked if he uses high-dose Parnate, but he has yet to reply.
Right now, I'm taking 40mg. I've been thinking about trying to add in Memantine to see if I can preserve the stimulant effect before I reach my target dose, but I am a little bit concerned about the moral conundrum of self-medicating. Is this something you have had to endure?
My other option would be to increase, slowly, to 60mg, under my psychiatrist's guidance and let him attend to the loss of any gains on the ADHD-front, though that thought leaves me somewhat depressed.