Posted by europerep on March 19, 2012, at 8:38:38
In reply to Re: Buprenorphine info-want experiences... » uncouth, posted by phidippus on March 18, 2012, at 19:55:30
> I started at a dose of 2 mg for the first day and titrated up to 4 mg the second day of use.
I just want to add a comment regarding dosage, for other members who come across this thread: for patients without opioid tolerance, 2mg is *WAY* too high as a starting dose. It can actually be dangerous at that dose, even if the potential for respiratory depression is not as pronounced as it is with other "typical" opioids.
In all studies and accounts of buprenorphine treatment for depression that I have come across, starting doses never exceed 0.2mg or maximum 0.4mg. Unlike conventional antidepressants, buprenorphine doses can be raised slightly more quickly, but this should also depend on how pronounced side effects are.
But again, for those who are reading this thread and contemplating using buprenorphine for depression: DO NOT start at doses above 1mg!
poster:europerep
thread:1013344
URL: http://www.dr-bob.org/babble/20120316/msgs/1013444.html