Posted by SLS on February 19, 2012, at 13:18:20
In reply to Re: opinions on this?, posted by Hugh on February 12, 2012, at 11:36:58
Thank you for this.
I don't think it is yet established how ketamine works to relieve depression. There must be something going on other than non-competitive NMDA receptor antagonism. Why wouldn't memantine work?
- Scott
> This slideshow has some interesting information on NMDA antagonists for pain relief. Skip to page 30 and it discusses how ketamine and magnesium work synergistically. So maybe even lower doses of ketamine would be effective if combined with daily usage of magnesium. The kind of magnesium discussed in the slideshow is IV infusion, but there' a new form of magnesium called magnesium l-threonate that, taken orally, can get more magnesium across the blood-brain barrier than an IV infusion of magnesium.
>
> Here's the slideshow about ketamine and magnesium:
>
> http://www.ndana.org/pdf/NMDAReceptorAntagonistslecture.pdf
>
> Here's some info on magnesium l-threonate:
>
> http://www.mit.edu/press/2010/magnesium-supplement.html
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1008851
URL: http://www.dr-bob.org/babble/20120212/msgs/1010838.html