Posted by novelagent on February 17, 2012, at 21:50:32
In reply to tardive akathisia, posted by Doc49 on February 15, 2012, at 12:49:34
> I have a patient with treatment refractory depression who has tardive akathisia from adjunctive aripiprazole. She has been off ari for several months and I have tried B blocker artane even reserpine without effect. She got the akathisia during her treatment for depression so a hair of the dog that bit you approach seems futile. Ideas?
>I also researched this by reading a book on wandering disorders, and it claimed donepezil had good results for akathisia, but it didn't seem to cite a specific study.
It appears there is evidence it is the prefrontal cortex that is involved, and not the stratum, which would explain why memantine and amphetamine also work... the research here lags far behind the anecdotal reports, in part because doctors are too often naively dismissive of any movement disorder complaints from antipsychotics to investigate the matter further. It's good to know someone cares.
poster:novelagent
thread:1010334
URL: http://www.dr-bob.org/babble/20120212/msgs/1010595.html