Posted by SLS on February 10, 2012, at 6:11:15
In reply to parnate agitation, posted by g_g_g_unit on February 9, 2012, at 20:10:57
> I've scaled my Parnate dose back to 5mg twice a day. I still feel noticeably irritable, angry/teary and stimulated after dosing.
>
> Would it make sense to scale back even further, or is it possible some tolerance might develop to these effects?
>
> I'm not particularly concerned with sparing myself discomfort. If there's logical reason to believe they'll abate, I don't mind sticking with this dose.
Do you think that things might actually get better at a higher dosage? Perhaps you need some pro-serotonergic activity to offset the anxiety, anger, and irritability being produced by stimulation of chatecholaminergic tracts. This would require the achievement of therapeutic levels of MAO inhibition, something you might not see until your reach 40 mg.* How about adding an anxiolytic temporarily?
Is there any bipolar stuff going on? If so, Depakote might help.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1009862
URL: http://www.dr-bob.org/babble/20120202/msgs/1009885.html