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Re: low dose prozac more effective AD than high dose?

Posted by linkadge on January 11, 2012, at 20:15:17

In reply to Re: low dose prozac more effective AD than high dose?, posted by godess on January 8, 2012, at 3:20:51

>the dose is 100mg in 1 go so the 100mg works its >magic all day. 50mg in the morning is not enough >even if topping up the other 50 mg at night. >does that sound weird to you

The problem is that the drug does not stay at a fixed concentration between doses. After the drug is fully absorbed, blood levels start to drop.

So even if you took 100mg in the morning, you would not have that same amount in your system in the evening. With really short half-life drugs, you need multiple doses each day or the blood level drops too low.

Paxil is eliminated the most quickly. However, prozac takes much longer to be eliminated.


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URL: http://www.dr-bob.org/babble/20120108/msgs/1007016.html