Posted by SLS on September 17, 2011, at 23:29:58
In reply to Re: 40% down to 25% » SLS, posted by Dinah on September 17, 2011, at 13:12:33
> For me, my problems generally stem from agitation and anxiety - perhaps some bipolarish tendencies. While Provigil may not cause wakefulness like it used to, it has the huge advantage of not causing anxiety or agitation in me.
> Nortryptiline was as very bad for me as Effexor and Wellbutrin. I have concluded that norepinephrine is something that doesn't agree with me.
That is very possible. Have you ever thought to take guanfacine? It is a NE alpha-2 agonist that suppresses NE, and is often used for ADD. The net effect is to improve function in the prefrontal cortex. This might explain why guanfacine is seen to reduce anxiety and improve attention. The thought just crossed my mind as I read your above post. Now that I have checked Google, I am very happy to report to you that my musings were accurate. Perhaps you can research it further.
> I wonder if those experiences you perceive as normal are something that can realistically be expected for a long period of time,
I don't see why not. Most people spend their whole lives feeling that way.
> since the longest period you've experienced them is six months.
I did more living in a day during those six months than I do in a year while ill.
> It occurs to me it might be something akin to the mild hypomania I often get with medications.
Actually, for me, my infrequent manic reactions to medication launches me into BP I type psychotic mania. I do not spend weeks in hypomania. It is an all-or-nothing severe mania. Thus, the six months I spent in a state devoid of psychotic mania represents a euthymic remission. Compared to severe depression, euthymia is nirvana.
There is a doctor near me who administers rTMS. I will consider paying him a visit if I do not respond to the next two antidepressant trials. Of course, I can't afford the treatments, so I might not have the luxury of choice.
Dinah, I appreciate your devoting some portion of your formidable brain-power pondering my plight.
Some see things as they are and ask why.
I dream of things that never were and ask why not.