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Re: Nardil anhedonia, Update » pedr

Posted by Conundrum on September 8, 2011, at 12:58:21

In reply to Re: Nardil anhedonia, need TCA? SLS?, posted by pedr on September 8, 2011, at 10:08:34

> > It seems that since I've started Nardil I've been more lethargic and lazy than normal. Usually I just want to sleep or do nothing. I find less interest in things that always helped my anhedonia a little like video games.
> >
> > I am wondering if things improve with a higher dose, or perhaps I should consider asking my pdoc on wednesday for nortriptyline, desipramine, or protriptyline to help with the anhedonia. I know he likes the stim + MAOI combo, but I have never had positive or pleasant experiences from stimulants.
> >
> > So does anyone have an idea what adding a TCA would do? I that this is part of your combo Scott.
>
> Hi, I have been on Nardil for some time now and experienced the same lethargy and anhedonia. Whilst Nardil was saving me from being in a very, very bad place, the somnolence and apathy wasn't/isn't great.
> I tried a swathe of adjuncts, mostly AP's and Stims to no avail. Lastly I have tried Abilify and found that even 2mg is too much. 1mg / day abilify and 60mg/day Nardil seems (touch wood, no predictions made) to be working pretty well for me. The abilify certainly helps with the lack of energy and motivation. It screws my sleep up even more than before but it's worth it.
> HTH

My Pdoc wanted to add a stim to Nardil, but I've never responded or tolerated them very well so I convinced him to let me try desipramine.

I'm just worried that if I try desipramine and if it kinda works and then I were to switch to nortripytline, which blocks receptors that historically my brain likes blocked, the reuptake effects would be a lot less potent, after being exposed to the more NE potent desipramine.

Hmm. Makes sense right?


Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual anhedonia. )
Country:USA
Currently taking 2.5 mg prozac, Multi B vitamin

 

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