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AP mechanisms of effect: Amisulpiride, sulpiride

Posted by floatingbridge on August 13, 2011, at 21:48:53

Hi I am attempting a comparison of some of the AP's out there.

I am looking for something that is tranquilizing, but does not
block dopamine (all those d2 and d3 things). At least too
much.

Any that effect kappa agonism however slightly. (Or maybe
that is nuts.)

Risperidone is sedating, which I like but I feel weighted and cranky, not great for depression. I have three more weeks at a low dosage to go. However, my anxiety is up, and I do not wish to increase my benzodiazepine intake.

At this point, I am researching.

(Abilify and seroquel were no-gos for me.)

Amisulpride and sulpride have appeared on the radar.

I admit to finding these comparisons difficult to do.

Any input regarding mechanisms of effect would be
appreciated, or a profile that might suit my complaints; MDD, anxiety the most plaintive.

Thanks.


I dig a pony.

 

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URL: http://www.dr-bob.org/babble/20110809/msgs/993693.html