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Does Tianeptine actually work? +Decreasing Saphris

Posted by uncouth on August 3, 2011, at 11:39:05

Hi folks,
I am doing yet another med switch and i'm expecting some mood instability on the downside. I live in the US and tianeptine isn't used here much but I have a big supply of it and in the past my doctor was relatively OK with us trying it.

I wanted to compile the latest thinking you guys have on whether tianeptine is an effective antidepressant in your experience. Especially if you've found it helpful for certain subtypes of depression, e.g. chronic depression, bipolar depression, anhedonia, etc. I hear that it has a low incidence of side effects. For me SSRIs and SNRIs have always felt a bit numbing and i'm not sure how good they have been for me in the long term. They certainly haven't done anything to measurably improve my life and if anything, may make me complacent when I really need to be making changes.

I have been reducing my dose of bupropion from 800mg to 600mg which i've been at for 7 days, and two weeks ago removed 30mg of cymbalta I had been taking. But what I'm really worried about is decreasing Saphris from 10mg to 5mg with the eventual intention of getting off of it completely. SO far the change has been negatively affecting my sleep but i'm wondering how the decrease in dose will affect my thinking. I haven't been totally off of an antipsychotic for an extended period of time in I think years. I'm hoping it will remove the feeling of being numbed to the world but i'm afraid of the depression getting really bad. I tried getting off of saphris completely 2 months ago and only lasted a week before I had to go back on because of sleep and mood issues.

Thanks, let me hear about your tianeptine experiences and if you have any comments on saphris or what it was like to go down on antipsychotics that would be good too.
Uncouth

 

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poster:uncouth thread:992701
URL: http://www.dr-bob.org/babble/20110728/msgs/992701.html