Posted by desolationrower on July 15, 2011, at 20:58:43
In reply to Can someone explain???, posted by Sheilac on July 13, 2011, at 7:09:48
> Ok - I know we have a lot of very smart people here and I was hoping someone could explain something to me.
>
> In the past (as we all know) I've taken Geodon. At first it was a GREAT antidepressant, but then it turned into hypomania then mania.
>
> Why would an anti-psychotic that is supposed to stop mania bring it on?
>
> If you're not mania BEFORE taking an anti-psychotic, WHY would it MAKE you manic?
>
> Are there chemicals in the brain it over stimulates?
>
> Thanks for any answers!
>
>well i think there are probably similarities to the increase of mood and energy of 'getting out of depression' and mania, as well as similarities to the 'mood dysregulation' of mania and depression. there are a lot of changes and some of them overlap, and some don't.
and yeah it hits several receptors so it can do various things. 5ht1a, nert, sert, 5ht2 all could be antidepressant, and i think all could be pro-manic (based on 'antidepressants' hitting those can increases manic risk)
i think the consensus is for antimania, the higher dose where it hits dopamine receptors is needed. or take a low dose with lithium or something.
-d/r
Better living through chemistry, socialism, and big phallic rockets (with a side of roquette)
poster:desolationrower
thread:990901
URL: http://www.dr-bob.org/babble/20110714/msgs/991118.html