Posted by SLS on June 4, 2011, at 5:15:41
In reply to Nardil: Placebo response? Am I nuts? Opinions plz, posted by zonked on June 3, 2011, at 23:54:52
> Either placebo is a VERY powerful drug or I am beginning to respond to Nardil therapy at day two. And only on 45mg!
>
> (This happened the very first time I was on Nardil - within a week it began to kick in.)
>
> Nothing dramatic, but I noticed I have started to enjoy music again. Verbal fluency is improved, and a friend of mine who saw me today noticed a change - he said that when I'm depressed I have trouble looking people in the eye...
>
> This very well could be a false alarm. I'll keep you guys posted.
>
> (For the record, this also happened to me when I started Zoloft therapy in 2001 - it started working within 3 days.)
>
> I guess what I want to know is: Does this mean anything clinically if this is a true AD response and not a placebo response? ADs are NOT supposed to take effect this quickly, are they? It isn't as though everything seems magic, perfect, and fixed (and that's not what I want anyway) - but
> I have felt more like myself today than I have in a LONG time. Not 100%, but significant.
>
> Hoping this is not a placebo response,
>
> -z
>
> Please, please let this continue. I need to start rebuilding my life...
It is very likely not a placebo response.Do not be surprised if your response fades in the short-term. Nardil can be activating at first. You should look at your early response as a positive "blip" that might very well indicate a stable response to emerge a few months from now. Some people don't experience a stable response to Nardil for four months. If you have nothing else promising to treat with immediately, you might as well stick with the Nardil. My first true success was using a combination of desipramine and Parnate. There are augmentation alternatives. Unfortunately, a doctor screwed up the works.
Currently:
Nardil 90mg
nortriptyline 150mg
Lamictal 200mg
Abilify 10mg
lithium 300mg- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:987065
URL: http://www.dr-bob.org/babble/20110529/msgs/987077.html