Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Regular Lithium: better than ER...

Posted by dragonblack on May 16, 2011, at 20:56:39

In reply to Re: How many are taking low-dose lithium? » floatingbridge, posted by SLS on May 16, 2011, at 9:20:15

I'm new to lithium, I've only been on it for 2 months, but I've been reading a lot about it. While titrating up, I've concluded that, for myself, I think I will be sticking with the regular form, rather than seeking the ER form, as well as once nightly dosing, regardless of doseage, as long as I can tolerate it.

Jim Phelps's site makes mention of single dosing resulting in a slight reduction in the risk of kidney problems. I also came across a medical text in google books (can't remember what) which reviewed Lithium studies and advocated once nightly dosing. The reasons stated were: 1) compliance was increased over split dosing, while preserving the mood stabilizing effect; 2) side effects were mitigated by virtue of the fact that peak plasma levels occurred in subjects' sleep, side effects were heaviest in the morning, a more "convenient" time, for most people, and thereafter lessened in severity during the day. 3) Finally, with once daily dosing, there is a reduced incidence of kidney problems, likely stemming from the fact that there is a window of time prior to the next dose (18-24 hours after a nightly dose) during which the kidneys get a reprieve, and such "rest" does not occur with split dosing.


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:dragonblack thread:985426
URL: http://www.dr-bob.org/babble/20110515/msgs/985493.html