Posted by linkadge on April 5, 2011, at 17:21:47
In reply to Re: Continuing Acytel-Choline discusion, posted by BrainDamage on April 5, 2011, at 15:05:40
>Obviously Acetyl-Choline isn't in itself "bad"
>Alzheimer sufferers have to little Acetyl-CholineAgain, I wouldn't really think of alzheimers as low acetycholine just as I wouldn't think of parkinsons as low dopamine. Alzheimers is a complex disease. There appear to be cholinergic deficits (as there are significant deficits in other neurotransmitter systems), but could be due to things like damage to cholinergic fibers or loss of producing cells. Also alzheimers is often comorbid with depression - which from a simplistic high/low acetylcholine model, would not make sense. Wouln't low acetycholine make the patients less depressed?
>Even people who get relief with Anti-choligenic >complain of poor memory & slow thoughts e.c.t.
Yes, and the cholinergic overdrive (if this exists) could simply be a result of a different biochemical imballance - ie. low monoamine transmission? low endocannabanoid transmission?
>I love coffee, which increases Acetyl-Choline
>Having said that other things that increase >choline do make me rapidly depressed.Coffee increases the release of acetycholine in certain brain regions. But again, its not a simple raise / lower effect. I think that long term high dose caffine use can depleate cholinergic stores.
Linkadge
poster:linkadge
thread:982007
URL: http://www.dr-bob.org/babble/20110321/msgs/982029.html