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Re: WARNING

Posted by mtdewcmu on March 23, 2011, at 16:33:23

In reply to Re: WARNING, posted by Conundrum on March 23, 2011, at 14:49:24

> > > Wonderful hope the pharmacist confirms and recommends what you have advised. Phillipa
> >
> > Whenever I have asked a pharmacist about drug interactions, they have always entered the combo into a computerized drug database. So they will probably be seeing the same thing I saw.
>
> Pharmacist said no problem taking 6 mg Emsam w/ nardil. Not sure why it wouldn't be completely cut out by then anyway.

I don't know if that pharmacist has access to better information than I do, but even on rxlist.com it says not to mix EMSAM and Nardil:

"Therefore, EMSAM should not be used in combination with selective serotonin reuptake inhibitors (SSRIs,e.g., fluoxetine, sertraline, paroxetine); dual serotonin and norepinephrine reuptake inhibitors (SNRIs,e.g.,venlafaxine and duloxetine); tricyclic antidepressants (TCAs,e.g.,imipramine and amitriptyline); oral selegiline or other MAOIs (e.g., isocarboxazid, phenelzine, and tranylcypromine);

"After stopping treatment with SSRIs; SNRIs; TCAs; MAOIs; meperidine and analgesics such as tramadol, methadone, and propoxyphene; dextromethorphan; St. John's wort; mirtazapine; bupropion HCl; or buspirone HCl, a time period equal to 4-5 half-lives (approximately 1 week) of the drug or any active metabolite should elapse before starting therapy with EMSAM."

It specifically says "other MAOIs" twice.

http://www.rxlist.com/emsam-drug.htm

Look under Warnings and Precautions.


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URL: http://www.dr-bob.org/babble/20110321/msgs/981000.html