Posted by creepy on January 19, 2011, at 12:43:47
In reply to Re: can anyone explain dopamine's role in depression? » creepy, posted by floatingbridge on January 17, 2011, at 13:17:36
I am on wellbutrin XL 150mg.. the sertraline Im on is a mild inhibitor at CYP2B6 I think, which wellbutrin uses. So Im effectively taking a little more than 150.
What Im having problems with is the hit-or-miss nature of taking this drug, its a lot like what amphetamine does to me. Some days its like taking speed, others its like a sugar pill.
Also just the fact that for 10 hours a day Im under its effects, and the other 14 Im not. Its hard to get out of bed in the morning. This is where desipramine really helped.
I have a lot of physical anxiety too. Im shakey and have butterflies in stomach feeling. Im sure it doesnt do my PTSD much good, but the depression is the big problem right now.
I have tried taking it with food, water. have tried making sure my heartburn isnt bad when I take it (acidity). Dunno what to try next. Doc wants to go back to the SR form but I worry about the mood / energy rollercoaster from that.
Wellbutrin certainly helps my depression but a pure NRI did about as much. The real difference is motivation which can feedback into depression relief. Im sure this is different for everyone though.
poster:creepy
thread:976349
URL: http://www.dr-bob.org/babble/20110115/msgs/977435.html