Posted by bleauberry on November 30, 2010, at 19:15:46
In reply to why didn't they prescribe this 10 years ago?, posted by linkadge on November 29, 2010, at 19:49:32
Link I think you are absolutely correct in everything you said and I am cheering at your wisdom. Wisdom I wish I had, but I'm at least glad to know someone who does!
I think at some point in the future they will look back at the 30-40 year era of SSRIs and conclude the whole thing was a cruel misguided joke. A result of the collision of politics, science, economics, arrogance, and ignorance.
In your case, you are getting a slight boost in serotonin, slight boost in norepinephrine, indirect slight boost in dopamine, and a slight boost in gaba, and control of any possible overexcitatory glutamate. I mean, you have all the bases covered.
Once in a while we see someone do extremely well on a pure ssri monotherapy. Maybe, what, 1 in 10? I can't explain those, nobody can, it just goes to show that the magic of the brain is far greater than mere humans can comprehend. But in general, those rare cases aside, my pure logic says that artificially increasing someone's serotonin alone without any attention to anything else is destined for trouble one way or the other...side effects, inefficacy, apathy, post-ssri syndrome, on and on. Pure logic tells me that if one neurotransmitter is low, they probably all are. There is so much interplay between them, and they share many of the same genetic and enzymatic processes along the way.
The tca's and benzos went generic a long time ago so there is no profit motive in them. They get shoved aside, with profit makers taking the lead.
Benzo tolerance and addiction are sometimes issues. But then, anyone who has done these drugs knows that SSRI tolerance (poopout) happens all the time, and SSRI withdrawals are a journey through hell.
Anyone who knows me knows that I am not in favor of large doses. Normal doses are too high in my opinion. If it takes that much, then it's the wrong med. Pure and simple.
Nice job. I like it.
poster:bleauberry
thread:971828
URL: http://www.dr-bob.org/babble/20101117/msgs/971995.html