Posted by morgan miller on October 21, 2010, at 22:42:35
In reply to adding lamotrigine, posted by Hunk20 on October 21, 2010, at 21:51:35
With the lithium and seroquel I personally think adding Lamictal is a bad idea. I would have gone for Lexapro or a good brand of St. John's Wort. Lamictal negatively impacts Long Term Potentiation. LTP is basically the long lasting communictation that takes place when two neurons are working together. It may have some involvement in long term memory and neuroplasticity. Lamictal also depletes your body of essential nutrients, mainly folate. If you take Lamictal, make sure that you take anywhere between 1.6 and 5.4 mg of l methylfolate, it may also help with your depression. I just think Lamictal should be avoided until all other options have been exhausted. I've read of too many reports of bad experiences with Lamictal and long term issues after stopping it.
I just don't see why a super low dose of something like Lexapro or a mild antidepressant like SJW could not be used given that you are taking a fairly high dose of Lithium and a potent mood stabilizing atypical anti-psychotic like Seroquel
poster:morgan miller
thread:946827
URL: http://www.dr-bob.org/babble/20101020/msgs/966537.html