Re: Dopamine

Posted by linkadge on September 16, 2010, at 8:57:11

In reply to Re: Dopamine, posted by Conundrum on September 16, 2010, at 7:21:44

Well, the first study you gave would equate to human doses of almost 2000mg of bupropion. The second study does not really give doses.
The following study suggests that the effect of bupropion on dopamine release is dependant on the dose (U shaped). Lower doses inhibiting it due to nicotinergic blockade, and higher doses facilitating it due to enhanced binding to the DAT transporter.
http://www.ncbi.nlm.nih.gov/pubmed/17477919

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