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Insomnia w/desipramine where there was none before

Posted by TriedEveryMedication on September 14, 2010, at 12:51:06

Hi Babble,

(I'm not taking this now, but I've been thinking about going on it again)

Desipramine used to help immensely with my ADD, but the sides were unpleasant so I would only be on it for a month or 2 at a time.

I would take it at night and it would knock me out for about 7 hours. I would wake up refreshed and jumping out of bed, ready to go. I took it a couple of times a year for several years.

Now, if I take it at bedtime, it keeps me up all night. If I take it in the morning, that night I fall asleep, but I wake up about 2 or 3am and can't sleep for an hour.

Any idea why a person's reaction to a drug like this would change?

And is there any way to combat this? Ambien doesn't really touch this insomnia.

BTW, other NRIs like strattera wake me up in the middle of the night, too.

Thank you.


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poster:TriedEveryMedication thread:962337
URL: http://www.dr-bob.org/babble/20100908/msgs/962337.html