Posted by linkadge on August 27, 2010, at 16:41:38
In reply to Re: Please explain?, posted by bleauberry on August 27, 2010, at 16:29:12
Most mood stabilizers are well known to be more effective in mania than in depression.
There are major unmet needs in the treatment of bipolar depression. Also, it is an area of major controversy (i.e. to use antidepressants or not).
I think that in classic bipolar disorder (i.e. major highs), there is evidence that mood stabilizers can prevent serious depression. It makes sense that preventing extreme mania would have some ability to lessen extreme depression.
OTOH, once the patient is "stabilized" mood stabilizers can tend to leave patients depressed.
Linkadge
poster:linkadge
thread:960165
URL: http://www.dr-bob.org/babble/20100821/msgs/960170.html