Posted by linkadge on August 7, 2010, at 22:39:42
In reply to Re: Ketamine IV yields swift AD Effect To Bipolar Pts » europerep, posted by Phillipa on August 6, 2010, at 14:15:47
Hard to know what the cognitive effects amount to. I know a lot of K users are polydrug abusers. The other issue is of dose and duration.
There may be a theraputic window. Lithium for instance can be highly neurotoxic above the theraputic level. It kills off brain cells when you go toxic.
I think there is a similar effect with NMDA antagonists. In lower doses, they are neuroprotective, in higher doses, they actually become excitotoxic. The effects in drug abusers therefore is hard to quantify.
Its just going to force many ill patients to the streets to obtain the drug in hopes of relief. It will be another 50 years till anything positive emerges from these studies.
Linkadge
poster:linkadge
thread:957361
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