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Re: Milnacipran 5th wk: no sex drive, physical sid » bleauberry

Posted by vic80 on June 15, 2010, at 18:07:03

In reply to Re: Milnacipran 5th wk: no sex drive, physical sid, posted by bleauberry on June 15, 2010, at 15:38:48

Hi Bleauberry,

Thanks for your reply. I value your suggestions given that your posts on Milnacipran inspired me to talk to my pdoc and get my prescription.

I did try the 25mg split thing - where I stay i could not find a chemist who could divide the capsule dose - so I ended up splitting open the capsule myself and taking 12.5mg twice daily. This hardly seemed to have much effect on me. Infact I started feeling darker and more panicked. SO a call to the pdoc - and I was asked to start 25mg twice daily - this definitely improved the depressive state - but as I explained in my post brought along a bevy of other problems - mainly a dazed feeling which makes me have feelings of disorientation, deja-vu, and weird body sensations.
I really am wondering if the norepinephrine is too much for me to handle.

- I have figured that I dont have much of the somatic signs of depression - I mainly have a low mood now which is accompanied with dysphoria in the morning - I cannot recall any particular increase or decrease in my energy levels. Its been the same.

I basically not feel I can function well when my mood if elevated - which is also scary for me coz of the increased cravings for alcohol and cannabis - intoxicants I have not used since a few years now. I have even experienced a craving for smoking - yet another habit I came out of 8 years ago.

I would not blame MIL for all this - my social situation too has changed - I no longer live with a 9 YO partner, plus my previous job is gone. So such stressors too contribute to my condition - even though these 2 were the reasons for it to appear in the first place.

I have an appointment with my pdoc on friday - I woukld have completed 5 weeks of MIL by then - I am really unsure of what to make out of my current situation whilst being on MIL. I have clearly felt a dumbing and numbing down of my brain - apathy and amotivation, and the sharpness of mind I once possessed. This could well be the lorazepam 0.5 mg I have been on for 2 months now.

All I can say is that the heightened emotionality I experienced at the beginning of MIL treatment was a welcome thing - it helped me feel the pain and live it rather coop it up and have panic attacks like I did previously. I had crying bouts - something which never happened in almost 6 years. All this felt nice - the escitalopram induced mental-numbing and derealization too had lifted. But that all could just be the dopamine rebound after stopping Lexapro.

A drug that would constantly give me the flu and make me sexually dead, make me feel disoriented, give me panic induced suicidal ideation et al - does not seem to somehow fit the bill of what I am looking forward to in terms of a helpful therapy.

I need something which is light - doesnt interfere with the acetylcholine, screw my sleep, or cause physical symptoms like the ones I have mentioned - more importantly I want to have full emotional range - no anxiety - I seem to be asking too much I guess!

What are your views if any on tianeptine
?

DO you feel I should still stick with MIL, how would a change to clomipramine be?

> The mood brightening effect you feel a few hours after dosing would continue if you took multiple doses. I don't mean 25mg three times a day. I mean, 25mg divided into 3 or 4 doses throughout the day. You are having too many peaks and valleys including the flu-like withdrawal symptoms.
>
> Just opinion, but yeah, I think you are getting too much of this drug. More does not universally mean better. More can be worse. What is normal for one person can be way too much for another. You've probably heard the saying "less is more".
>
> I know I sound like a broken record, and I apologize if my opinions are not taken well, but I still feel this entire trial has been poorly managed. No wonder all the problems.
>
> Much less of a dose, divided into multiple doses. That's what you need to do before throwing in the towel on this thing.


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poster:vic80 thread:951052
URL: http://www.dr-bob.org/babble/20100615/msgs/951167.html