Posted by SLS on May 21, 2010, at 5:20:16
In reply to Re: Immipramine Causes Natural Endorphins to Drop, posted by linkadge on May 20, 2010, at 18:05:53
Thank you, Linkadge. I thought it was just me.
- Scott
> Not sure I follow, the study said that chronic treatment with the drug inhibited neutral endopeptidase. Nowhere does the study say this causes endorphins to drop.
>
> It could be the other way around, perhaps increased opiate production is a consequence of remission, and that endopeptidase simply increases to metabolize the extra opiate production.
>
> In this study, neutral endopeptidase actually lowers the levels of substance P. Substance P inhibitors have antidepressant potential. So perhaps the upregulation of neutral endopeptidase actually lowers upregulated levels of substance P in limbic regions.
>
> http://gut.bmj.com/content/52/10/1457.abstract
>
> Its complex and this guy is reading too much into things.
>
> Linkadge
>
>
>
>
>
The measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:948058
URL: http://www.dr-bob.org/babble/20100514/msgs/948147.html