Posted by Katgirl on April 28, 2010, at 9:57:49
In reply to Re: Multiple drug exposures and treatment resistence, posted by Bob on April 26, 2010, at 20:44:19
I'm coming in very late to the conversation, but I too am treatment resistant and/or treatment intolerant. I can't take any of the SSRI's anymore. I definitely had a great response to SSRI's at first (felt great/normal on Paxil, it was like a wonder drug at first).
After having improvement with rTMS I decided not to do further drug trials because they just seemed to make the situation worse and worse.
I definitely know that my brain chemistry has been permanently changed, whether from taking Paxil or from going through withdrawal to paxil, I don't know. And its not just psych drugs. When I would get the stomach flu, the only thing that could stop me throwing up was compazine. Besides making me stop throwing up, it always made me feel relaxed and "dreamy". I haven't taken compazine in years (since the withdrawal etc) until this fall in the hospital after surgery. Every time they gave me a dose of compazine, I would get shaky and my muscles would feel "too tight" (hard to explain, it was a really weird feeling--I would start clenching my jaw). I also react differently to my inhaled steroid nasal spray and a host of other medications. Sigh.
I was hoping that the rTMS would "reset" my brain in terms of medications, but the fact that I still react to these other drugs differently leads me to believe it didn't.
I will not be trying any medications until something new comes out that is not an SSRI. But that is a luxury I have, because I have some stability/functionality due to the rTMS. Before I found rTMS, I kept trying the drugs and trying the drugs, because as Scott said earlier, what other choice do you have?? I was suicidal and non-functional. I SO wish I had known about rTMS before I did all those drug trials that made me worse and worse and worse. I can't help but wonder how differnt my life would be if I had gotten rTMS right away after the paxil withdrawal and subsequent lapse into a severe, suicidal, agitated clinical depression.
poster:Katgirl
thread:944856
URL: http://www.dr-bob.org/babble/20100425/msgs/945412.html