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Re: Potential Nardil poop-out. Feeling cheated.

Posted by bleauberry on April 13, 2010, at 16:32:07

In reply to Re: Potential Nardil poop-out. Feeling cheated. » bleauberry, posted by pedr on April 12, 2010, at 22:02:35

One more thought came to me last night. Though I am not confidently schooled on it, I am aware that Nardil has a significant impact on vitamin B6 metabolism. Which of course is key in many bodily functions including making neurotransmitters. I wonder if that could be involved? It might be worth trying B6, or better yet, p5p (the version of B6 that our bodies metabolize B6 into), a combo of both, and some general B vitamins to support it all.

> > I guess your question could be asked by millions of people on various drugs. It isn't just nardil. Wish we knew why things don't just stay good once they get there.
>
> Too true. I just don't get it though. I wonder why whatever changes have taken place that make me feel better would start undoing. I mean, MAOI's crush MAO and AFAIK don't stop doing so just because you've been taking the med for x months. Maybe the brain dynamically compensates in some way, reducing or changing receptors or releasing different or less neurotransmitters. Who the feck knows.
>
> >
> > Here is something to consider. It may be relevant and maybe not.
> >
> > Ever since the nardil reformulation, and generics, there have been hundreds, probably even thousands of complaints from patients. Maybe there is some efficacy fluctuation from one batch to the next? Maybe you were getting a version of nardil by one particular manufacturer for all those months but recently were substituted a different one?
>
> I thought that too but all of my bottles of Nardil have come branded from Parke Davis. Still doesn't rule out variation in composition of course but it makes it less likely I would have thought.
>
> Cheers,
> Pete


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