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Re: TCA's With Opioid Actions?

Posted by bulldog2 on April 11, 2010, at 14:54:10

In reply to Re: TCA's With Opioid Actions?, posted by hopefullynow on April 11, 2010, at 14:24:43

> Hy Bulldog,
>
> I get pain relief at 25 mg clomi the next day at the beginning of treatment but it seems that the higher dose the greater analgesic effect.So maybe for acute pains one should target 75-100 mg/day.
>
> You could titrate Anafranil (brand, made by Novartis), it comes in pills of 10 mg which have triangular form and 25 mg which are round.They're preety small, but with a razor you can cut them easily in half.
>
> Compared to amitriptyline, clomi is more anticholinergic than antihistaminic and I found it easier to tolerate at comparable doses.I have a better tolerability to anticholinergics that to anti histamincs but overall, anafranil was easier to bear.

Thanks for the info..so if i'm on 30 mg of amitriptyline I might use 25 mg of clomipramine to start. I might ask my p-doc if I can get the 10 mg pills as that is how I like to titrate. First goal is to work up to 50 mg. From what I've read this med is potent at both se and ne. A doctor Gillman rates it as the best antidepressant. For me start low and proceed low is the best option.
Thanks again for the info.I have dog clomicalm at home. Unfortunately she has passed away. Dog clomicalm is Clomipramine. Capsules are 75 mg.
I don't know if my insurance would cover anafranil as they want generic. Any generic pills out there. they all seem to be capsules.
Bulldog2

 

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poster:bulldog2 thread:942955
URL: http://www.dr-bob.org/babble/20100406/msgs/943100.html