Posted by ed_uk2010 on April 3, 2010, at 11:20:08
In reply to Doxepin and small ammont Prozac together, posted by gerri on April 2, 2010, at 20:40:25
Rather than restarting fluoxetine (Prozac), I think that you should consider taking a different SSRI such as sertraline (Zoloft), citalopram (Celexa) or escitalopram (Lexapro) instead. These medications are chemically different to fluoxetine but have similar benefits. Personally, I would be tempted to go for sertraline.
Doxepin increases serotonin levels minimally, certainly not to the extent of an SSRI. Combining sertraline, citalopram or escitalopram with a low dose of doxepin (eg. 25mg) should be OK. Now that your urticaria symptoms have improved, you should be able to start reducing the dose of doxepin eg. from 100mg to 75mg to 50mg to 25mg (then add sertraline). Even at low doses, doxepin is a potent antihistamine and reduces urticaria. Alternatively, if you don't need the doxepin anymore, you can stop it completely before starting sertraline. Like all antidepressants, doxepin should be stopped gradually. For your current (milder) symptoms, a non-sedating antihistamine may be sufficient. Cetirizine is particularly useful for urticaria.
poster:ed_uk2010
thread:941908
URL: http://www.dr-bob.org/babble/20100328/msgs/941972.html