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Re: Sertindole and Abilify and Seroxat SAFE?????????

Posted by Brainbeard on March 11, 2010, at 14:09:59

In reply to Sertindole and Abilify and Seroxat SAFE?????????, posted by Jeroen on March 10, 2010, at 3:49:41

Sertindole's QT-prolongation is dose related, so you could try and find the lowest effective dose. It has a long half-life, so it may take some time to figure that out.

SSRI's can also dose-dependently prolong QT-interval, although it's more rare.

I don't know about the Abilify - doesn't it leave the QT-interval alone? Otherwise this doesn't seem to be a risky combination to me. Throwing in a TCA or another med that significantly prolongs QT-interval, that would be risky. I wouldn't take more than 20mg of Seroxat just to be sure. Certainly not more than 40.

Practically no medication is totally safe. You could have an EKG to rule out trouble - couldn't you?


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URL: http://www.dr-bob.org/babble/20100305/msgs/939166.html