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Re: Spontaneous Hypertensive Crisis on MAOI » stargazer2

Posted by George Romero on February 27, 2010, at 17:11:26

In reply to Re: Spontaneous Hypertensive Crisis on MAOI, posted by stargazer2 on February 27, 2010, at 15:18:28

> Are you sure it wasn't from something you ate or drank (alcohol or caffeine) or another medication?
>
> I was not aware of anything called spontaneous, not related to some other factor that could have been overlooked.
>
> What dosage were you on?
>
> I had a reaction on Nardil with a stimulant, a tiny dose but I did have Nifedepine and used it successfully. I dropped to the floor with my BP cuff on my arm. It was scarey but I got through it and continued on Nardil, so that didn't make me have to switch as that is devastating when you are stable on something.
>
> I would try and convince my doc to give it another try and make sure you have Nifedipine, handy. I htink a second chance is worth it but that is me and my pdoc, so it is an individual call. MY doc knows me so well he knows I will not take any risks at all. I wouldn't be convinced that it was not something I hadn't eaten, drank or another medication in combination, like an OTC cold medication, those are big NO-Nos. Unfortunately when on a MAO, you forget what goes into your mouth until you have the dreaded reaction.
>
> I've been on MAOs for years and only had a real reaction once, with a few mini ones, that showed me how careful you have to be with anything you put in your mouth and ingest. Many people can not be that disciplined. But if it means you could die, you have to be vigilant.
>
> Good luck with whatever happens with this issue.

Thanks for your comments. I was on 20 mg at the time (10 mg twice per day). I thought about it a lot, and I can't think of anything I took or ate or drank that day except coffee, which i've been drinking everyday prior and since the episode with no problem. i hadn't taken any other meds (OTC or otherwise). i know i ate some food the day before that could have contained tyramine but doc says the reaction is much more immediate than that--no more than an hour or two after ingesting the a forbidden food--so it couldn't have been that. (admittedly, he doesn't know much about MAOIs or tyramine or spontaneous hypertensive episodes, so if you guys have different information, please let me know.)


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poster:George Romero thread:938043
URL: http://www.dr-bob.org/babble/20100216/msgs/938115.html