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Re: New combo - Good Luck Sailor!

Posted by Brainbeard on February 20, 2010, at 15:53:02

In reply to New combo, posted by linkadge on February 20, 2010, at 12:30:30

I'm on this same combo currently, except for the methylphenidate, and I'm also taking 1800mg of gabapentin. (So effectively I'm on a rather different combo.)

I'm hoping to have methylphenidate prescribed again some day, but that will have to wait for now. It was a rather harsh drug for me anyway, but it was able to give me some euphoria, enhanced social functioning and a better ability to perform boring tasks. For motivation and drive, 2.5-10mg of selegiline actually worked better for me.

Now that I'm rambling away anyway, I'm planning to increase my amitriptyline because of chronic pain that is not properly addressed by the gabapentin, and also because amitriptyline is a marvelous drug in my opinion, once you get over the antihistaminergic threshold. It's an inverse 5HT2C-agonist, which comes down to it being a 5HT2C-antagonist, and a 5HT2A-antagonist, which all means more dopamine and noradrenaline, good, deep sleep and a healthy appetite. It's dirty and good.

I read some reports lately by the way - like I said, I started rambling anyway - about some cases of people using amitriptyline recreationally in doses of up to more than 800mg at a time! I didn't even know it was possible to take such doses without deceasing. Not that I'm planning to imitate this irresponsible behavior.

Linkadge: Good Luck Sailor!


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poster:Brainbeard thread:937465
URL: http://www.dr-bob.org/babble/20100216/msgs/937482.html