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Re: Can lithium carbonate cause anger/rage? » SLS

Posted by Tomatheus on December 23, 2009, at 15:43:18

In reply to Re: Can lithium carbonate cause anger/rage? » Tomatheus, posted by SLS on December 23, 2009, at 14:04:53

Scott,

Thank you for your post. I have tried N-acetylcysteine, and it worsened my agitation and irritability. As far as my diagnosis is concerned, the most recent one that I have is schizoaffective disorder, depressed type. The only reason I'm taking Lamictal is because the antidepressants that I've tried either don't work like they did in the past or make matters worse in one way or another. The Lamictal helps with my depression and cognition some at 12.5 mg, but worsened my depression when I tried 25 mg. Abilify also makes my depression worse at doses higher than what I'm taking. Because Dekapote made me feel more depressed and Lamictal worsened my depression at 25 mg, I'm not big on the idea of trying Trileptal, but I appreciate the suggestion.

Tomatheus

> Have you thought to add NAC (n-acetylcysteine) as an antioxidant? From the drugs you list, I am guessing that there is some bipolar stuff going on? NAC is currently being investigated for the treatment of bipolar disorder. Preliminary results are encouraging.
>
> For the irritability, you might want to try using Trileptal as an additional mood stabilizer. Although Tegretol is the drug most referred to as a treatment of irritability, aggression, and impulse control, Trileptal (cousin of Tegretol) is being used more often. I have seen it work well for a few people. Unlike Tegretol, it is not sedating, and does not require frequent blood tests to screen for agranulocytosis.
>
> Propranolol is sometimes used to treat tremulousness and anxiety, particularly anticipatory anxiety. It, too, can help with irritability, but can also produce depression. You might want to investigate pindolol as a treatment for the tremulousness as well. My only concern with this drug is that it might increase irritability. You'll have to research that.
>
>
> - Scott


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URL: http://www.dr-bob.org/babble/20091217/msgs/930568.html