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Re: switching from venlafaxine/mirtazap to moclobemide europerep

Posted by SLS on December 23, 2009, at 13:06:30

In reply to switching from venlafaxine/mirtazap to moclobemide, posted by europerep on December 23, 2009, at 12:39:08

My first reaction is to say that moclobemide usually is not a very effective drug. It can produce improvements as early as in the first week, but one is always having to raise the dosage to maintain the effect until it finally stops working. I haven't seen too many people profit from moclobemide for more than a few months. You are better off trying Nardil or Parnate if you want to pursue MAO inhibitors.

If venlafaxine is partially effective, you might want to add nortriptyline or bupropion to it before discontinuing it. If you are to discontinue venlafaxine and/or mirtazapine, you really should taper them rather than stopping them abruptly. The withdrawal effects can be severe. Perhaps you can begin to taper the mirtazapine while adding nortriptyline or bupropion to the Effexor.

- Scott




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