Posted by bulldog2 on December 6, 2009, at 9:13:55
In reply to Re: Parnate Good Drug - Wrong Time, posted by bleauberry on December 6, 2009, at 7:44:16
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> >
> > It was so nice after the third day to find I wanted to listen to music again which I had lost interest in.
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> Yeah, me too. I am a really good guitarist, but wow I got amazing on parnate by day 3.
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> > I think your right about norepinephrine. I get that side of being cold on drugs such as strattera. I was on parnate for 8 weeks in April. I guess I was more resiliant at that time. I got up to 60 mg. The cold feeling and insomnia abated after about 6 weeks. The ad effect lasted for a decent amount of time after discontinuing. At that time I incremented 5 mg at a time which I will try again. I'm med sensitive.
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> I'm sensitive too. That's why my doses were only 2.5mg.
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> > The cold is rough right now because the weather has become cold and raw. Also had a hip repl in sept and the weather plus the parnate is not to pleasant on the recuperating leg.
> > But you have a good pt on the all or nothing approach. Our docs give us medication level goals and we often quit if we can't meet they're therapuetic level goals. We may still get something out of lessor levels. I've heard of some achieivng remission on 10 mg of parnate.
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> I got these ideas from other people.
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> My Lyme doctor has patients doing well on stuff like 1mg Lexapro? Yeah, 1 mg. His patients are notoriously med sensitive...that is itself I think is a clue there is something going on.
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> At Lyme forums, most people do not take herbs or meds continuously for mood improvement. Instead, they take them as-needed to fit the day, the time, the demand, whatever. A lady might be on SAMe for a couple days, SJW for a couple weeks, B vitamins for a week, Ritalin for a day, some obscure Chinese formula for months...each person has discovered through their own battles what helps, what doesn't, and when they help...usually not all the time, but at specific times.
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> Let's assume for the sake of an example that you are 100% better on 10mg Parnate but the side effects are too much to live with.
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> Let's assume you are 60% better on 5mg and side effects are more tolerable.
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> Let's assume you are 30% better on 5mg taken once every two days and side effects are low.
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> Let's assume you are 0 % better on 0mg Parnate.
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> Well, any of the above scenarios look...in my eyes...to be better than 0mg parnate. Over time, the side effects should lessen, allowing a higher dose if needed. And you are correct, people have found remission in 10mg Parnate. It usually takes a few months to really settle in, but it happens. Sometimes I think our doctors erroneously have us overshoot our needed dose...thus creating a new chemical imbalance the opposite of the one we started with...we blew right past the balance point, right past our magic window. Sometimes I wonder if too much is as bad as not enough. I think it is common actually. But that's just me. I see things in ways most people don't.
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> I don't know about anyone else, but given a choice of the above options, I would take a 30% gladly versus no improvement. It's obviously not the ultimate goal, but for now, it is very welcome.
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>To many doctors take a cook book approach to meds. They haul out that heavy pdr and look up the dosage levels. Maybe these dosages are averages that fit most cases but also may be to much for some. You're right in that to much in fact may be as bad as to little. I wonder how many med failures are caused by aggressive dosing where the patient quits because of intolerable sides. The doc often refuses to try a smaller dose and think outside the box. Treat patients as individuals and not use a cookbook approach to dosing.
Years ago when prozac burst on the scene my primary doc was an internist and a pharmacologist. He voiced concern to me about the standard 20 mg starting dose and was there really a need to boost serotonin so aggressively.He related a story to me about an elderly patient who chipped a bit of amitriptyline from a 25 mg pill now and than for her depression and it worked. Most doctors would never think of such a plan or endorse it.
In the
poster:bulldog2
thread:928144
URL: http://www.dr-bob.org/babble/20091206/msgs/928308.html