Posted by mtdewcmu on November 25, 2009, at 13:54:53
In reply to Re: I'm taking Abilify » mtdewcmu, posted by jparsell82 on November 23, 2009, at 14:12:50
>
> I just came across this study the other day:
>
> http://www.ncbi.nlm.nih.gov/pubmed/17455104
>
> Shows Abilify helps counteract the weight gain of Remeron and Remeron helps counteract the akathisia of Abilify.
>Unfortunately, that is not a very good study. It is practically impossible to draw conclusions from an open label study. The difference in efficacy they found between remeron plus abilify and remeron alone did not achieve statistical significance. And, although they claim that "the addition of aripiprazole to serotonergic antidepressant treatment options such as SSRIs or mirtazapine obviously results in a more rapid improvement of depressive symptoms in TRD," I see no sign that they determined whether the decreased latency of effect was statistically significant. Perhaps the other studies they cite there show an "obvious" improvement. But I would not base any kind of treatment decision on this study.
poster:mtdewcmu
thread:925843
URL: http://www.dr-bob.org/babble/20091117/msgs/926946.html