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Re: Nardil dosage questions... » gagesa

Posted by ace on October 31, 2009, at 23:41:51

In reply to Nardil dosage questions..., posted by gagesa on October 31, 2009, at 21:22:06

> Hello, I'm new to this site in the hopes that I might be able to get an answer or two that other boards aren't able to help me with.

Welcome! You are in the right place. Wonderful and very educated people here.


> I started Nardil 5 weeks ago. 1 week on 45mg and 4 weeks on 60mg. I feel no difference yet.

Titration far to slow.


My next doc appointment is in early December. So I will know for sure whether or not the 60mg will work for me. We had already discussed going up to 75mg if the 60 is not working. Although my doc is familiar with the drug, he has never prescribed it to any other of his patients before, only to me after years of failed med attempts. So neither of us have any real world experience to base some of my questions on, only text book info.
> Lets say I do need to go up to 75mg, how long should I be on it to give it the maximum amount of time before I can decide whether or not it is working? I was going to give it either 6 or 8 weeks, mainly due to not wanting any major side effects and giving it the full chance to kick in.

OK, as I stated you have titrated Nardil far too slowly I feel. Once reaching the dose of 60mg, you have stayed at this for too long.

After much reading and experience with the drug I advise:

1st 3 days: 30mg (15mg bid (twice a day))
Next 4 days: 45mg (15mg tds (thrice daily)

Any pronounced side effects drop back to 30mg

Week 2: Stay put on 45mg

Then push dose up to 60mg (15mg QDS (4 times a day), if no response after 6 weeks, go straight to 90mg (not 75mg).

Split the 90mg dose into 30mg tds (3 times daily)

Now this is very important in the initial stages of Nardil therapy:

1. Take your doses at the same time daily.
2. Split your doses as advised above.
3. Do NOT drink any alcohol or take any illicit drugs.

In your case, I most certainly would go straight to 90mg now. Please understand that you must be patient, you may have to give it 12 weeks max.
The old MAOI's have to do a lot of work! And they almost always take longer than SSRI's and even TCA's.
I feel the payoff you recieve will be well worth your patience!!!

> One more quick question, Ive read so much about this maintenance dose thing. Half the posts say they take it, the other half don't take it, just take their regular full dose. I cannot understand this?

Don't try to understand it. Once you recieve a good response STAY AT THAT DOSE!!!!


> I would greatly appreciate any info from either current nardil users, or past users with experience with the drug.

I am the Nardil Champion here!

Please feel free to ask more, and be patient with Nardil.
Give it time to work it's majic!

Peace,
Ace:)


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