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Re: TD and masking » delna

Posted by jane d on October 30, 2009, at 18:25:32

In reply to Medical mystery. Any experts? Scott? HELP!, posted by delna on October 30, 2009, at 7:31:52

> I know that reducing dopamine in one of the brain DA pathways (as a result of APs) can lead to TD but have never heard of a AP helping with a movement disorder (like my sensation that vanished with Geodon).... In fact it makes them worse!
>
> Also when I look at the binding actions of Geodon, apparently dopamine antagonism only happens above certain doses and I was on 40- 60mg only.


Delna,
I have read of AP's temporarily masking TD symptoms. As I recall TD symptoms would appear the AP dose would be increased and they'd disappear for a while. Then they'd reoccur and the dose would get raised again causing them to temporarily disappear again. Disclaimer - it's been seven or eightyears since I've looked at anything to do with TD.

I'd think that the studies showing Geodon only binding above a certain dose were done on a typical population but you already know that you are not typical. Certain groups (people with certain types of disorders) are also more likely to get TD.

I'm sorry if that sounds discouraging in what is already an awful situation. If you're satisfied with the credentials of the researchers you found, perhaps you can contact them directly. This sounds rare enough that they should be happy to find another sufferer.

Good luck,

Jane


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URL: http://www.dr-bob.org/babble/20091029/msgs/923555.html