Posted by Pheepho on October 16, 2009, at 21:00:18
I am currently on Moclobemide 900mg which I take in one dose in the am. I was previously taking it as a divided dose, but after discontinuing Zyprexa I found I couldn't sleep, wondered if it was the moclobemide, and tried taking it all in the morning. After 5 months of pretty severe depression and anxiety that occured every morning and resolved later in the day, which my doctor attributed to a biological depression, I finally made the connection with the moclobemide. The depression seemed of shorter duration over time, and I finally realized it always occured about 30 minutes to 1 hour after taking the moclobemide. If I postponed taking it til lunchtime, I would have a good morning, but a dip in my mood early afternoon.
I don't have an appointment with my doctor til next week, but I have started weaning myself down to 750mg. My doctor is alright and I think will realize I need to wean down if I am getting this reaction.
Just wondering if others have experienced this kind of adverse reaction, and other experiences with moclobemide weaning (what should I expect?).
Now I don't know how much of the hell I have gone through over the past 5 months was Zyprexa withdrawal, and how much was an adverse effect from the moclobemide. I was on moclobemide for about 18 months before discontinuing Zyprexa, and I didn't notice an adverse reaction but I guess was always battling with some depression. I wonder if the Zyprexa was kind of masking the problem with the moclobemide. It gets difficult to figure out what's going on when you are on more than one med. I am currently on 125mg of quetiapine to help me sleep, but I wonder if I will need this if I can get off moclobemide.
poster:Pheepho
thread:921193
URL: http://www.dr-bob.org/babble/20091012/msgs/921193.html