Posted by floatingbridge on October 10, 2009, at 10:47:14
In reply to what pharmacies are likely to have it in stock?, posted by iforgotmypassword on October 9, 2009, at 22:29:27
I'm only intruding to add that I did begin to get mild akathisia at the 5-10 mg dose. My thumbs and hand would twitch, and at ten, I felt like I wasn't able to smile correctly--my mouth would grimace. Is that akathisia? It completely resolved once removed from abilify. You seem incredibly knowledgable--but maybe Emme's advice is sound.
fb
> it wasn't even on the system at the loblaws superstore drugstore pharmacy near me. should i call a hospital pharmacy?
>
> i've decided i am going to try it, but i'm going to find where i put my lorazepam in this messy apartment first.
>
> i think i am likely going to take a dopamine agonist with it, likely pramipexole, as that is covered by the ontario drug benefit. aripiprazole's agonism at dopamine autoreceptors suppresses dopaminergic firing in the VTA significantly, which i think is at the root of its akathisia and EPS issues. with the autoreceptors occupied and little dopamine release, a dopamine agonist may be able to fill in some of the gaps that cause akathisia, since lower dose aripiprazole seems likely to leave some dopamine receptors open, which may also lower the possibility of D2L receptor upregulation, and lower the chance of tardive dyskinesia as well.
poster:floatingbridge
thread:920190
URL: http://www.dr-bob.org/babble/20091001/msgs/920376.html