Posted by bleauberry on October 8, 2009, at 16:39:25
So after outpatient surgery I was given Hydrocodone, 2 every 3 hours for pain. Knowing the slippery treacherous slope of opioids, I have only been doing 1 to 1 1/2 during an entire 24 hour period.
The effect took me by surprise. I expected to be maybe heavily drugged, sedated. Or maybe to get euphoric, but my luck is never that good. What actually happened was that I felt absolutely completely normal, like 20 years ago before illness hit. No depression, no high, no nothing. Just pure normal.
My hypothesis is that, as Larry pointed out, the toxins of infectious organisms have an affinity for the opioid receptors, thus displacing our own natural opioids from attaching to those receptors? I am sure hydrocodone has stronger affinity to those receptors than the toxins, so it displaces them. Normalcy is the result. Remove the toxins, depression gone. Nothing at all to do with serotonin or any of the stuff the psych drugs target.
So now the likely impossible challenge is to find what will bind or neutralize those toxins. In Stephen Buhner's Herbal book for Lyme, Sarsaparilla is one of very few substances that strongly binds toxins in the blood. Dr Zhang has a formula of Chinese medicines to partially do that as well. And it makes me wonder about LDN...maybe that's why I had such a roller coaster ride on it...feeling not much different while the receptors were blocked, feeling randomly much better as the increased opioids hit the receptors, and feeling worse as the toxins moved in to displace the opioids. ???
Well I guess this could be arm-chair quarterbacked from here to the moon. I just wanted to say that low dose hydrocodone equals normalcy for me. That's a bad road though.
I wonder about Tramadol? Doctors prescribe that like candy. SNRI with some opioid action. Horrible withdrawals too though.
Even when we know from where our depression comes and what will fix it, it doesn't always make anything any easier.
poster:bleauberry
thread:920192
URL: http://www.dr-bob.org/babble/20091001/msgs/920192.html