Posted by delna on October 6, 2009, at 1:34:09
In reply to Re: being 'out of it' » delna, posted by Sunbath on October 4, 2009, at 16:06:56
Hi Delna,
>
> thanks for your message.
>
> It's very difficult since in my country they only prescribe stimulants only for very very severe disorders.. it's not commong at all to prescribe them for treating some side effects caused by other medications!That's too bad :( because one of Provigil's off-label uses ( and for which is commonly used)is for drug induced sedation. Also it has approval for shift workers who are sleep deprived. Here is an article about its off label uses. Although the title sound really bad there is a line in there stating that it is used for druginduced sleepiness http://www.news-medical.net/news/2007/10/28/31791.aspx
> It was even difficult to get my doc to prescribe partnate in the first place.. Parnate is considered very exotic in my country and it's even unavailable over here (had to import it).. I really don't know if it's possible to get a prescription of Provigil...
I too have to import it.
> I know there aren't any alternatives to parnate except maybe Nardil, so I will keep trying hard. If this daytime sedation won't pass I will try to get a Provigil subscription.. but I'd have to pay for it on my own since my insurance won't cover it, because I'm not suffering from serious narcolepsy which is the only real indication for it over here..That sucks. Nardil is more sedating than than Parnate apparently. May I ask why you are taking Parnate in the first place? Have you tried The SNRI's and failed with them? Provigil and Wellbutrin can easily be added to them and there are studies showing this
> I think they are too much concerned about possible abuse or addiction to stimulants..
>What do you think about that?Provigil is not addictive in my opinion but the patients info leaflet says it has potential to be so. http://www.provigil.com/media/PDFs/patient_info.pdf
Read the conclusion of this article about tolerance and dependence of Provigil- it is positive.
http://www.ncbi.nlm.nih.gov/pubmed/16737742?ordinalpos=32&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSumWell its not addictive like the traditional stimulants at all, I believe. In my experience it is not addictive anyway. You can stop it cold turkey without any side effects.
>Can you tell provigil's effects apart from parnates?
Yes for sure. It makes all the difference.
>Does one develop tolerance to it?
I haven't and I have been taking it for a few years.
> I could get parnate legally over a freind who is MD and who could write a prescription for me. I wouldn't like that since I'd like my pdoc to agree on that matter, but maybe if anything fails I would consider it.. what would you think?
Personally I would take it especially if it is a low dose. But I understand you wanting your pdoc to give the nod of approval. maybe it is safer considering Parnate is such a drug wherein drug-drug interactions are common and you need to be monitered.
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> However yesterday I took 20mg before sleep and I slept like a baby so maybe it's working!
> I was much more clear headed during the day without taking my doses during the day!
>
Good to know!> How are you doing? Did you increase your dose?
Haven't increased yet, In fact may withdraw because it has too many drug interactions which my doctor didn't bother to tell me about and frankly Parnate takers need to be monitored and given all the information. Also, after having one good day, I have started getting suicidal again. Embarrassed as I am about saying this, it is also making me oversexed (not part of the bipolar because I don't have any other hypomanic symptoms)
>How's your sleep? If you are still suffering from insomnia.. are you going to consider a sedating antidepressant -maybe a serotonine antagonsit- as a sleep aid? I think considering insomnia is the most common side effect of parnate- it might be necessary.. what do you think?
>
My sleep is fine but then again I am a sleepy person by nature. also I take clonazepam at night to sleep.> I wish you all the best!!
thank you..I wish the same for you!
Take care
DPS: Here is an article speaking of adding traditional stimulants to Parnate. Old but looks promising:
http://www.ncbi.nlm.nih.gov/pubmed/3997787?ordinalpos=12&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
poster:delna
thread:919533
URL: http://www.dr-bob.org/babble/20091001/msgs/919904.html