Posted by SLS on September 14, 2009, at 16:45:24
In reply to Discontinuation: How do you know?, posted by zana on September 14, 2009, at 15:52:04
Hi Zana.
Your treatment regime looks like quite a mess, although I imagine there was logic involved with adding each drug.
How have you gone about tapering your medication?
I am not sure how to resolve the difference between withdrawal rebound and relapse as you describe your experiences at this point. (I am guessing that imaging studies could differentiate between them). The temporal relationship between discontinuation and the emergence of depressive symptoms might provide a clue. Obviously, the longer the depressive symptomatology persists, the more likely it is to be relapse, especially if other withdrawal effects have come and gone.
Maybe you should get rid of the Remeron first. That would leave Seroquel in place to continue to provide histamine H1 blockade and prevent rebound insomnia and anxiety. I would then attempt to discontinue the Risperdal. You then might want to bring nortriptyline in before getting rid of the Seroquel. This might replace the 5-HT2a antagonism of the Seroquel and the NE reuptake inhibition of the Seroquel metabolite to prevent relapse.
- Scott
poster:SLS
thread:917067
URL: http://www.dr-bob.org/babble/20090912/msgs/917076.html