Posted by SLS on August 25, 2009, at 13:27:19
In reply to Re: Post SSRI Sexual Dysfunction » SLS, posted by Phil on August 25, 2009, at 9:43:29
> Any proof of this?
Great question. Keep us honest. :-)
When someone responds well to an SSRI, and that SSRI poops-out and never works again, this is the result of changes in the brain, right? It's called tachyphylaxis, and you should be able to find citations regarding this on Google. A similar phenomenon is sometimes seen with lithium. There are articles on Medline that refer to this phenomenon as being lithium-induced lithium refractoriness. Look for RM Post as the author.
I don't have any evidence to provide you regarding the persistence of sexual dysfunction after SSRI discontinuation. I just never looked into it.
> I've been on meds 25 years and don't 'feel' that much has changed. Hard to tell but if changes have occurred, they are subtle.
There is only one effect that comes to mind that I have had persist after drug discontinuation. I have had an exaggerated cremaster reflex upon orgasm. This began after I took my first antidepressant drug, imipramine. It does get better when I respond favorably to treatment, leading me to believe it is an autonomic effect.
- Scott
poster:SLS
thread:913953
URL: http://www.dr-bob.org/babble/20090818/msgs/914023.html