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First time Parnate -- common side effects?

Posted by Girlnterrupted78 on August 20, 2009, at 22:47:02

I have treatment resistant depression. I just got started on Parnate, which is my 2nd MAOI after Nardil failed.

I started Parnate 1 week ago. First two days on 10mgs, next 3 days on 20mgs, next 3 on 30mgs, and I'm starting on 40mgs tomorrow.

So far so good, but I can see two side effects already: hypotension AND physical weakness with daytime sleepiness.

Are these the common Parnate side effects? I thought Parnate was more of a stimulating med rather than sedating, like Nardil. Am I wrong?

Today, I tried to do my daily 3-mile-run, and it was almost impossible because of how weak I felt. My legs felt heavy and I felt kind of sleepy/tired, not very in the moood for running, although I had just programmed my 3rd run of the week and it usually goes very well.

In the end, I barely ran half of it and a lot slower than usual. Is this common on Parnate, and do you know whether this will go away?

And the hypotension is bad. Every time I get up from a chair or from bed, my head gets very very hot and I start to feel light-headed, things turn dark, and I almost lose consciousness. I can handle that for a while, as long as it doesn't last forever. I remember on Nardil it lasted 2 months or so, so I'm fine. But I'm more worried about the weakness/sleepiness. How long will that last?

Also, will Parnate help me socially? This is my biggest issue of all. I need to become a social being because I have serious anxiety/avoidance/irritability problems. One other med turned me into a social butterfly magically (Celexa) but pooped out after a year.

Can Parnate reproduce the amazing social results I got from an SSRI?

Thanks for any info.


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