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Re: depakote and anger

Posted by hopefullynow on August 20, 2009, at 8:51:30

In reply to depakote and anger, posted by deerock on August 17, 2009, at 22:40:03

Hy, Depakote caused the same reaction to me.I had been diagnosed with GAD and slight bipolar, so after trying a lot of AD's, benzos and so, I decided to have a trial of divalproex at 500mg/day plus 2mg Klonopin taken at night, no AD or other psy med.The first few days I felt dizzy, a little bit nauseated and somehow social friendly but with that I noticed an increased anger and iritabillity.Like more confident I felt, more cranky I was.After one week I had to stop, it were too much, the anger was unbearable, arguing and swearing all day long, an strange sensation of dizinhibition, hypomania type.Go figure, just the opposite effect that I waited for.The other thing that scared me a lot was that the anger came with an deep depression (suicidar ideation), so i stopped cold turkey and after 2-3 days things returned to (not so good but tolerable)normal.The same reaction happen with an similar trial with phenytoin and topiramate.Better results I've had/have with an relative small dose (200-400 mg)of old and good long lasting carbamazepine taken at bed with 2 mg Klono.Hope that helped.

> hi, i am on day 4 of depakote. im up to 750 mg per day. i dont know what my diagnosis is. i think its panic disorder and GAD but i think i have some BPD symptoms as well, although whenever i ask if I have that nobody ever confirms that i do.
>
> anyhow, since i started the depakote, i feel more angry. today i slammed the door in my therapists office and threw a cup of tea all over the bathroom.


>
> ive been dealing with anger issues but i have never acted out like that in her office in 2 years...and i go 3 times per week.
>
> i think it may be the depakote, of course my pdoc says it probably isnt. has anyone heard of this kind of reaction? maybe i should go down a dose.

 

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