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Re: Some encouragement? Pristiq » Zana

Posted by Amelia_in_StPaul on June 16, 2009, at 15:15:23

In reply to Re: Some encouragement? Pristiq, posted by Zana on June 16, 2009, at 14:05:00

Thanks for the reassurance about wired/tired lessening. I'm glad to hear it. Some nausea kicked in, and my eyes feeling sort of dilated, I'm not sure that's the correct way to describe it, but I'm tolerating all this better than I thought I would. Suppose we'll see tonight, though. I do take Trazodone, so I hope it will see me through.

There is a family history of schizophrenia--my sister. My OCD started as an obsession that I would become schizophrenic. I think these thoughts are probably part of that, but one never can tell. It wouldn't bother me so much, except that she has had this condition for 20 years and has not much improved, even on medication. So it's hard to see and I have a huge fear of it.

Have you tried Trazodone before? I'm sure you have, but I was just curious. I know lots of people take Seroquel for sleeping, and anxiety, but I couldn't tolerate even that tiny dose. I am considering Abilify. I guess I worry that my dopamine receptors will get supersensitive, and that I will never be able to be off an AP. Actually, my depression was not that bad when I first went on an AD. Now I cannot live without ADs.

I don't know, I think your doc may be right. I've learned in the last two years just how much my depression and anxiety are caused by my thoughts. I just wish that I wasn't so d@mn sensitive to meds. On the other hand, I am tolerating Pristiq better than I thought. But this is day 1. I've taken meds where the side effects got worse after the first day. Well, we'll see...

thanks for your encouragement, Zana

> I am taking remeron, seroquel, pristiq, provigil, klonopin, gabapentin and resperal. I have tried all the other APs except zyprexa and found some of them, I think actually maybe only abilify to be of some help but only for a short time. This is all for treatment of major depression.
> The experience you describe of being wired and exhausted at the same time is very typical of SSRI's ,less so with SNRIs. As you know, pristiq is a mixture, an SSRI/SNRI. That is usually an early side effect and should lessen. But yeh, I've certainly had the feeling that I was both exhausted and wanted to go to bed but sure I couldn't sleep and also the feeling of not sleeping at all when in fact I was getting some sleep. I've never done OK on an SSRI without a sleep med. That's what the remeron was originally tried for. Then my pdoc ramped it up hoping to get some AD effect which never emerged, then we added seroquel which had a modest AD effect, then the pristiq and my pdoc was then reluctant to reduce the remeron since there is some literature about the combination of remeron and pristiq being effective.
> I doubt very much that you are becoming schitzophrenic. Is there any family history? It sounds like you are right that what you are experiencing is part of your OCD. My pdoc put mr on reparidal because she thinks all depression is a kind of yhought disorder. I don't know if shes right or not and I don'y know wht seroqul wouldn't cover that bot, oh well, that's how I am taking 25 meds - just feels like 25.
>
> Zana


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URL: http://www.dr-bob.org/babble/20090611/msgs/901333.html