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Re: Lamictal XR » SLS

Posted by yxibow on June 6, 2009, at 0:51:29

In reply to Lamictal XR, posted by SLS on June 5, 2009, at 16:21:58

> The FDA approved an extended release version of Lamictal for once daily dosing on June 1, 2009. I think someone here already mentioned it.
>
> I know there are going to be some people who will say that this is no more than a patent extender. However, I think you will find droves of people who say differently after having migrating from Welbutrin IR to SR to XL.

In this case I would say iffy -- all extended releases and extended extended releases and metabolite releases and disintegrating tablets and depot injections, etc, are patent extenders including Wellbutrin SR, XL. That's just a matter of economics.


However, Wellbutrin SR showed definite signs of less seizure risks and I would have never wanted to be on IR. So there are some that actually "made the grade" in psychiatric circles.

Lexapro also has a bit of a reputation for being the "cleanest" of SSRIs even though its just modified Celexa. Can't say it was 'clean' for me.

Seroquel XR, it really hasn't been heard of that much.

Lamictal.... I don't know... I take Lamictal once a day in the morning anyhow, but I take 250... its mostly for antisuicidal thought /antidepressant augmentation. I have known of someone who takes 600, I dont know if it is split.

So a modest dose may not be needed to be XL'd through the day with the plasma level.

> As for me, I am hoping that my insurance company will cover the Lamictal XL if the script is written for that specifically.


Seroquel XL required a prior authorization from unnamed insurance provider.

I couldn't say if it did anything one way or the other -- on one hand it may have helped smooth breakthrough symptoms at night, on the other hand it did do something wierd.... I don't know, changes in my polypharmacy can do good, or odd things.

So I decided not to continue.


> Does anyone have an idea as to how long it will take for pharmacies to get Lamictal XL?


Well they have a blank web page and a domain registered by GSK back in 2006 expiring soon (like they won't renew it) if that means anything, which Seroquel XR had for months so I would say a 4 month lead probably.


> Right now, I am taking the Mylan generic version of lamotrigine at 500mg a day. I had been fine on the name brand GSK Lamictal at 200mg a day. Even at 500mg, I am still short of feeling well on the generic.

I think I'm taking the Teva one. The diamond splits aren't quite even, but whatever.


http://www.drugs.com/imprints/9-3-463-13381.html


Well -- I don't know if it is the generic, Scott, or just effectiveness in general. But you're the judge of that. Like I mentioned before, there are people who take more. And things could have changed biologically since.

But I do agree if, and if, you only made one change, and it dramatically did something different, then maybe it is the last thing done.

-- Jay

 

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poster:yxibow thread:899557
URL: http://www.dr-bob.org/babble/20090531/msgs/899632.html